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BBC seminar series

Thursdays, Mission Bay, Genentech Hall Auditorium 12:00-1:00 PM, simulcast to Parnassus, Medical Sciences, S-161

Academic Year 2013

Date Speaker Topic Host
9/27/12 Sheng Zhong, U Illinois Comparative Epigenomics: a case study of human, mouse and pig pluripotent stem cells. Bo Huang
10/11/12 Caleb Bashor Clements Lecture Wendell Lim
10/18/12 Dianne Newman, CalTech New interpretations of ancient biomarkers: exploring the functions of (2-methyl) hopanoids, steroid analogs in bacteria Joe Kliegman
10/24/12 Stuart Schreiber, Harvard University Braisted Lecture, Cancer genetic dependencies targeted by small molecules Jim Wells
11/8/12 Doug Lauffenberger, MIT In Vivo Systems Analysis of Cell-Cell Communication and Signaling in Inflammation Kathy Giacomini
11/15/12 Robert Lamb, Northwestern Activating protein re-folding to cause paramyxovirus-mediated membrane fusion Bill DeGrado
11/28/12 Greg Verdine, Harvard Cancer Chemical Biology Jim Wells
11/29/12 Sunney Xie, Harvard Life at the Single Molecule Level David Burkhardt
1/10/13 Susan Marqusee, UC Berkeley Sequence Determinants of a Protein's Energy Landscape Henry Lin
1/17/13 David Odde, University of Minnesota Microtubule self-assembly kinetics Wallace Marshall & Dyche Mullins
1/24/13 Wenying Shou, Fred Hutchinson Cancer Center War and peace: a biological basis for population segregation and mixing Wallace Marshall
2/7/13 Jonathan Javitch, Columbia A tale of two substrates: a novel mechanism for neurotransmitter:sodium symport Robert Edwards
2/14/13 Michael Levitt, Stanford Combinatorial Methods Solve a Difficult Structural Problem to Reveal How Chaperonins Work in Eukaryotes John Gross
2/21/13 Bridget Carragher, Scripps Investigating the dynamics of molecular machines using automated electron microscopy Bob Stroud
2/28/13 David Liu, Harvard Small-molecule and macromolecule discovery driven by evolution Zev Gartner
3/7/13 Michael Laub, MIT Specificity and evolution of bacterial signaling pathways. Anthony Shiver
3/14/13 Celeste Nelson, Princeton Physical control of tissue morphogenesis Zev Gartner
4/11/13 Brenda Schulman, St. Jude Children's Research Hospital Twists and Turns in Ubiquitin Conjugation Cascades John Gross
4/18/13 Garry Nolan, Stanford A structure for cancer and immunity at the single cell level by mass cytometry Justin Rettenmaier
4/25/13 Adrian Keatinge-Clay, University of Texas Visualizing and harnessing polyketide assembly lines Bob Stroud
5/2/13 Laura Kiessling, University of Wisconsin-Madison Probing and Perturbing the Cell's Glycan Coat Kevan Shokat
5/16/13 Jeffrey Skolnick, Georgia Tech Interplay of physics and evolution in the likely origin of protein biochemical function Peter Cimermancic

Academic Year 2012

Date Speaker Topic Host
9/29/11 Vijay Pande Some surprises in the Biophysics of Protein Dynamics Emmanuel Yera, Jain Lab, Computational Student Group
10/13/11 Jure Leskovec Computational Perspectives on the Structure and Information Flows in On-Line Networks Michael Fischbach
10/13/11 Jure Leskovec, Stanford TBA Michael Fischbach
10/20/11 BP Clements Best Thesis Talk, Anselm Levskaya Closed Loop Optogenetics for the Study of Neural Circuitry In Vivo Chris Voigt
10/27/11 Jim Ferrell, Stanford Dissecting the Mitotic Trigger Wendell Lim
11/3/11 Adam Cohen, Harvard TBA Bo Huang
11/17/11 Galit Lahav, Harvard Encoding information through protein dynamics Wendell Lim, Center for Systems & Synthetic Biology
12/1/11 Doug Lauffenberger, MIT Quantitative Cell Bioengineering Analysis of EGF Receptor Inhibitor Effectiveness in Cancer Therapeutics Kathy Giacomini, QBC Sponsored
12/7/11 Tom Tuschl Characterization of regulatory small RNAs and RNA-binding proteins Michael McManus
1/12/12 Ivan Ovcharenko, NIH NCBI Computational strategies for deciphering the sequence encoding of gene regulatory elements Mee J Kim, Ahituv Lab
1/19/12 Kristala Jones Prather, MIT Parts, Devices, and Chassis in Support of Metabolic Engineering David Booth
1/26/12 Robert Austin, Princeton Darwinian Evolution: Not As Slow as You Might Think Wallace Marshall
2/16/12 Mina Bissell, LBNL Why don't we get more cancer? The proposed role of the microenvironment in tissue specificity and breast cancer Crystal Nyitray, Student
2/23/12 Amy Palmer, University of Colorado Developing fluorescent tools for live cell imaging Xiaokun Shu
3/1/12 Rami Hannoush Chemical tools to perturb and image Wnt signaling Danica Galonic Fujimori
3/15/12 Harmit Malik, Fred Hutchinson Cancer Center Genetic conflicts: the usual suspects and beyond John Gross
4/5/12 Ian Wilson, Scripps Broad neutralization of HIV and influenza viruses Bob Stroud
4/12/12 Michelle Chang, UC Berkeley Building new chemical function in living organisms Jack Taunton, Kevan Shokat
4/19/12 Alan Engleman, Farber Cancer Center Retroviral integrase function and drug resistance mechanisms Bob Stroud, HARC Sponsored
4/26/12 Howard Hang, Rockefeller Chemical Reporters for Protein S-Palmitoylation in Cell biology and Innate Immunity Danica Galonic Fujimori
5/3/12 Russ Altman, Stanford The emerging network of data for linking genes and drugs Chris Wen, Giacomini Lab, Computational Student Group
5/17/12 Jennifer Lippincott-Schwartz, NIH Mitochondria, metabolism and cell cycle control: an imaging perspective Amanda Silber and Si-Han Chen, Students
5/24/12 Ira Mellman, Genentech Next Generation Approaches to Basic Cell Biology & Drug Discovery Justin Rettenmaier, Wells Lab
5/31/12 Jim Ferrell Dissecting the Mitotic Trigger Wendell Lim
5/31/12 Jim Ferrell Dissecting the Mitotic Trigger Wendell Lim
5/31/12 Jim Ferrell, Stanford Dissecting the Mitotic Trigger Wendell Lim

Academic Year 2011

Date Speaker Topic Host
9/30/10 Ehud Isacoff, UC Berkeley TBA Pam England
10/14/10 Quincey Justman, BP Alum TBA Kevan Shokat
10/21/10 Amy Keating, MIT TBA Tanja Kortemme
10/28/10 Bill De Grado, Braisted Talk TBA
11/18/10 Bonnie Bassler, Princeton TBA Joe Kliegman
12/2/10 Lei Wang, Salk Institute TBA Jack Taunton
1/13/11 David Case, Rutgers TBA Tom James
1/20/11 Hening Lin, Cornell TBA Danica Galonic & Jack Taunton
1/27/11 Adrian Elcock, University of Iowa TBA Andrej Sali
2/3/11 Erik Winfree, Cal Tech TBA Felix Moser, Voigt Lab
2/17/11 Jonathan Eisen, UC Davis TBA Peter Skewes Cox and DeRisi Lab
2/24/11 Ning Zheng, University of Washington TBA Jack Taunton
3/3/11 Charalampos Kalodimos, Rutgers TBA Gross Lab, Robin Aglietti
3/17/11 David Price, University of Iowa TBA HARC Center, Alan Frankel
4/14/11 Mark Yeager, University of Virginia TBA HARC Center, Yifan Cheng
4/21/11 CANCELLED: Niles Pierce, Cal Tech TBA Hana El Samad
4/27/11 Chris Chen, U Penn TBA Tejal Desai and Sai Duriseti
4/28/11 Bill Noble, University of Washington TBA Genevieve Erwin, Pollard Lab
5/5/11 Eduardo Perozo, University of Chicago TBA David Julius
5/12/11 Bruce Roth, Genentech TBA Brian Shoichet
5/19/11 TBA TBA
5/26/11 Alexander Van Oudenaarden, MIT TBA
6/2/11 Linda Hsieh-Wilson, Cal Tech TBA Al Burlingame and Samuel Myers

Academic Year 2010

Date Speaker Topic Host
10/1/09 Jeremy Wilbur, Clements Recipient Clements Distinguished BP Award Talk: Mechanisms for Scaling the Mitotic Spindle
10/15/09 Alice Ting, MIT TBA Orion Weiner Lab, Sheel Dandekar
10/22/09 Bill Jorgensen, Yale TBA Matt Jacobson
10/29/09 Mark Mayer, NIH TBA Dan Minor
11/19/09 Niko Grigorieff, Brandeis TBA Yifan Cheng
12/3/09 Rachelle Gaudet, Harvard TBA Lily Jan
1/14/10 James Berger, UC Berkeley TBA Dan Minor
1/21/10 Andy McCammon, UCSD TBA Ken Dill
2/11/10 Gerald Joyce, Scripps TBA Mike Lopez and Kevan Shokat
2/24/10 Louise Jonson, Oxford TBA Bob Stroud, HARC Sponsored
2/25/10 W.E. Moerner, Stanford TBA Matt Jacobson
3/11/10 Angela Gronenborn, University of Pittsburgh TBA John Gross, HARC Sponsored
3/18/10 Susan Taylor, UCSD TBA Matt Jacobson and Jim Wells
4/1/10 Daniel Herschlag, Stanford TBA Babbitt Lab, Michael Hicks
4/15/10 Jon Ellman, UC Berkeley TBA Charly Craik
4/22/10 Edward Holmes, Penn State TBA Andino Lab, Cecily Burrill
4/29/10 Peter Sorger, Harvard TBA Philip Merksamer, Papaz Lab
5/13/10 Phil Cole, Johns Hopkins TBA Danica Galonic Fujimori
5/20/10 Danny Tawfik, Weizmann Institute of Science TBA Brian Shoichet
5/27/10 Erik Sorensen, Princeton TBA Brian Shoichet
6/3/10 Eric Gouaux, OHSU TBA Rob Edwards

Academic Year 2009

Date Speaker Topic Host
10/2/08 David Savage Clements Talk: The Carbon Cycle at a Molecular Level: Design Principles of Cyanobacterial and Yeast Metabolism
10/16/08 Jamie Williamson, Scripps Ribosome assembly: watching a machine assemble in vitro and in cells using mass spectrometry S. Floor
10/23/08 Bruce Cohen, LBNL-Biological Nanostructures Facility of the Molecular Foundry Smart Nanoparticles and the Future of Bioimaging Lily Jan
10/30/08 Ruben Gonzalez, Columbia Coupling of ribosome and tRNA dynamics during translation elongation
11/13/08 Sharad Ramanthan, Harvard "Deforming signaling networks: using evolutionary analyses to re-wire kinase pathways." H. El-Samad
11/20/08 Jean-Louis Reymond, Univ. of Berne Switzerland "Exploration of Chemical Space for Drug Discovery by Database Generation" B. Shoichet
12/11/08 A. Joshua Wand, University of Pennsylvania The dark energy of proteins: Conformational entropy and its contribution to molecular recognition by proteins C. Mcclendon
1/15/09 James Chou, Harvard The Proton Channels of Influenza Virus John Gross
1/22/09 Anand Asthagiri, Cal Tech "From molecular networks to multicellular phenotypes" Hana El-Samad
1/29/09 Tom Muir, Rockefeller Testing the ‚Histone Code‚Hypothesis Using Synthesis
1/30/09 Benoit Roux, University of Chicago QB3/iPQB Invitational Speaker Series Dill and Jacobson Labs
2/12/09 Richard Friesner, Columbia Computational Modeling of Protein-Ligand Interactions: Successes, Challenges, and Prospects. Matt Jacobson
2/19/09 Chris Miller, Brandeis Chloride transporters and chloride channels all mixed up Dan Minor
2/27/09 Sumit Chanda, Burnham Institute Global Analysis of HIV host-pathogen interactions using RNAi Frankel Lab
3/12/09 Bryan Roth, UNC, Chapel Hill Synthetic and chemical biological approaches for modulating neuronal signaling in vivo Brian Shoichet
3/13/09 Uri Alon, Weizman Institute of Science QB3/iPQB Invitational Speaker Series El Samad Lab
3/19/09 James Chen, Stanford Chemical probes of embryonic signaling and patterning
3/20/09 Jeff Kelly, Scripps Research Institute QB3/iPQB Invitational Speaker Series Shoichet Lab
4/2/09 Joachim Frank, NYU Ribosomal Dynamics during Translation Rebeca Choy
4/16/09 Wes Sundquist, University of Utah The Biochemistry of HIV Budding Alkan Frankel
4/23/09 Vern Schramm, Albert Einstein College of Medicine Enzymatic Transition States: Drugs and Dynamics. Danica Galanic Fujimori
4/24/09 Ian Haworth, USC QB3/iPQB Invitational Speaker Series Sali Lab
4/30/09 Deborah Hung, Harvard TBA
5/14/09 TBA Braisted Lecture
5/21/09 Annelise Barron, Stanford Robust, non-natural Aupeptoid, Au mimics of antimicrobial peptides for potent, selective bacterial pathogen killing Ken Dill
5/28/09 Andy McCammon, UCSD TBA
5/29/09 Aviv Regev, Broad Institute QB3/iPQB Invitational Speaker Series Weissman Lab
6/12/09 Steven Boyd, University of Calgary QB3/iPQB Invitational Speaker Series Majumdar Lab

Academic Year 2008

Date Speaker Topic Host
10/11/07 Nick Endres, UC Berkeley Clements Talk: Using artificial lipid membranes to gain insights into the structure and function of signaling proteins in the EGFR/Ras signaling network D. Agard
10/18/07 Justin Gallivan, Emory University Reprogramming Bacteria with Small Molecules and RNA P. England
10/25/07 Jack Szostak, Harvard Medical School Braisted Lecture: Towards the Design and Synthesis of an Artificial Cell C. Craik and J. Wells
11/1/07 Peter Wright, Scripps Exploring the protein energy landscape: Disorder, dynamics, and protein function S. Miller
11/15/07 Paul Hergenrother, University of Illinois Using small molecules to identify novel targets for the treatment of cancer J. Taunton
11/29/07 David Baker, U Washington Novel enzyme catalysts, rapid structure determination, and pushing the limits of folding and design with a multiplayer online computer game J. Wells
12/13/07 David Deamer, UC Santa Cruz Nanopore analysis of DNA K. Dill
12/20/07 Lewis Kay, University of Toronto Seeing the invisible by solution NMR spectroscopy T. James
1/3/08 Rob Phillips, Caltech How Cells Decide What to Eat and Where to Go W. Marshall
1/10/08 Tom Knight, MIT TBA R. Williams
1/17/08 Tom Wandless, Stanford A General Solution to the "Problem" of Chemical Genetics J. Taunton
1/24/08 Gaudenz Danuser, Scripps Integration of mechanical and chemical signals in cell migration deciphered by global fluctuation analysis W. Marshall
2/14/08 Eric Siggia, Rockefeller University Predicting the course of evolution H. Li
2/21/08 Susan Marqusee, UC Berkeley TBA K. Dill
2/28/08 James Inglese, NIH Chemical Genomics Center Integrative Technologies Enabling Chemistry and Biology as a Public Resource for Chemical Probe and Drug Discovery B. Shoichet
3/13/08 Gavin MacBeath, Harvard University TBA
3/20/08 Ned Wingreen, Princeton Modeling the chemotaxis network of E. coli C. Tang
4/17/08 Tudor Oprea, University of New Mexico From Digital to Experimental Bioactivity: Exploring novel estrogen receptors B. Shoichet
4/24/08 Richard Ebright, Rutgers Single-molecule analysis of transcription G. Narlikar
5/1/08 Vishva Dixit, Genentech, Inc. The Inflammasome & Deubiquitinases in Innate Immune Signaling J. Wells
5/15/08 Rachel Brem, UC Berkeley Expression variation and regulatory feedback K. Dill
5/22/08 Jagesh Shah, Harvard Medical School Biophysical measurements of mitotic checkpoint signaling: How cells prevent chromosome loss W. Marshall
5/27/08 Gary Ruvkun, Harvard University TBA
5/29/08 Brian Chait, Rockefeller University Protein Interactions as a Window into Cellular Function A. Krutchinsky
6/5/08 Gerald Crabtree, Stanford Designing small molecules to regulate protein interactions

Academic Year 2007

Date Speaker Topic Host
10/12/06 Mathew Francis, UC Berkeley New chemical tools for site-selective protein modification P. England
10/19/06 Adrian Keatinge-Clay, UCSF Dissecting, deciphering, and designing polyketide assembly lines R. Stroud
10/26/06 Christopher Walsh, Harvard Andrew Braisted Lecture, Halogenases: Natural product tailoring enzymes C. Craik
11/2/06 Ron Weiss, Princeton Synthetic biology: from bacteria to stem cells C. Voigt
11/16/06 Jay Keasling, UC Berkeley Engineering microorganisms for production of inexpensive, effective, anti-malarial drugs C. Craik
11/30/06 Sarah O'Connor, MIT Biosynthesis of new alkaloids in periwinkle K. Shokat
12/14/06 Maurizio Pellecchia, Burnham Institute A million little pieces: Fragment based approaches to drug discovery M. Jacobson
1/11/07 David Weitz, Harvard Reconstituted networks as models of cell mechanics W. Marshall
1/18/07 Richard H. Kramer, UC Berkeley Engineering light-activated ion channels for remote control of neuronal activity R. Edwards
1/25/07 Edward Egelman, University of Virginia Polymorphic perversity in polymers: The biological role of multiple subunit interfaces in helical filaments D. Mullins
2/1/07 Christina Smolke, Caltech Engineering molecular sensors for probing and programming cellular systems H. El-Samad
2/22/07 Alice Ting, MIT New protein labeling methodology and application to single molecule imaging of receptor trafficking with quantum dots J. Wells
3/1/07 Lorena Beese, Duke An integrated view of DNA polymerization and repair R. Stroud
3/15/07 Wilfred van der Donk, University of Illinois Chemistry and biology of ianthionine synthesis J. Taunton
4/12/07 David Tirrell, California Institute of Technology Non-canonical amino acids in protein engineering and proteomic analysis P. England
4/19/07 Brenda Bass, University of Utah dsRNA binding proteins in RNA editing and RNA interference J. Gross
4/26/07 Adrian Gross, Northwestern Structural aspects of potassium channel function B. Shoichet
5/10/07 Pei Zhou, Duke University Medical Center From novel antibiotics to fast NMR J. Gross
5/17/07 Melissa Jurica, UCSC Spliceosome structure by cryo-EM reconstruction G. Narlikar
5/24/07 Phil Baran, Scripps The catalytic cycle of discovery in total synthesis A. Renslo
5/31/07 William Bialek, Princeton Physics problems in early embryonic development R. Fletterick
6/7/07 Luc Jaeger, UC Santa Barbara Exploring folding, assembly and design principles of RNA as a proto-language A. Frankel

Offered by the UCSF Graduate Division
Administered by the UCSF School of Pharmacy
Delivered by faculty members in the UCSF School of Pharmacy and the UCSF School of Medicine

NIH
Supported by the National Institutes of Health

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