genetics

Ahituv study provides new insights into enhancer gene regulation

Research led by UCSF scientists has provided fresh insight into the operation of DNA sequences in the genome that regulate gene expression.

Child’s illness fuels lab team’s search for early-life epilepsy diagnostics

The lab of UCSF School of Pharmacy faculty member Nadav Ahituv, PhD, studies how abnormalities in DNA segments that control the activity of genes could lead to diseases. Recently, researchers there have begun applying that focus to seeking a genetic basis and diagnosis for an epilepsy of early...

Ahituv asks why some DNA is ultraconserved

Research by Nadav Ahituv, PhD, faculty member in the UCSF School of Pharmacy, shows that laboratory mice that had specific sequences of their DNA removed eat, grow, and reproduce normally. The stretches of DNA deleted by Ahituv are referred to as ultraconserved DNA that have been protected...