bacteria

Fischbach joins project to generate drugs from bacterial genomes

Bacteria generate small molecules to fend off their fellow microbes. They also produce molecules that affect the response of host organisms—including humans—to their presence. Such molecules have been a major source of antibiotics, immunosuppressants, anti-cancer agents, and other drugs.

Fischbach and Desai focus on “micro” solutions to improve health with drugs

Faculty members in the Department of Bioengineering and Therapeutic Sciences, UCSF Schools of Pharmacy and Medicine, share their research on the human microbiome and microfabricated drug delivery systems and their hopes for how their science will improve the health of patients.

Reflection: 30 years of top NIH funding for UCSF School of Pharmacy

Table of contents

Introduction
Budget significance
Reasons for past success
A decade of funding for bioinformatics
New drug discovery directions attract support
Research stalwarts draw funding for decades
New directions in translational research attract support
Expansion of the School’s...

Logic gates allow bacteria to work like computers

Logic gates, similar to those that form the basis of silicon computing, can now be inserted into bacteria via genetic engineering, making it possible to manipulate bacteria to perform complicated tasks. This finding will ultimately enable cells to be programmed with more intricate functions,...